- Kick-off
- Venue
- New Era Field
Head to head, from our own archive
Buffalo Bills and San Francisco 49ers have met 6 times on this desk, first in 2001 and most recently in 2020. Buffalo Bills have won 3, San Francisco 49ers 3. Aggregate score 126–137.
08.12.20
NFL
San Francisco 49ers
Buffalo Bills
24
34
16.10.16
NFL
Buffalo Bills
San Francisco 49ers
45
16
07.10.12
NFL
San Francisco 49ers
Buffalo Bills
45
3
30.11.08
NFL
Buffalo Bills
San Francisco 49ers
3
10
26.12.04
NFL
San Francisco 49ers
Buffalo Bills
7
41
03.12.01
NFL
San Francisco 49ers
Buffalo Bills
35
0
San Francisco 49ers
Buffalo Bills
24
34
16.10.16
NFL
Buffalo Bills
San Francisco 49ers
45
16
07.10.12
NFL
San Francisco 49ers
Buffalo Bills
45
3
30.11.08
NFL
Buffalo Bills
San Francisco 49ers
3
10
26.12.04
NFL
San Francisco 49ers
Buffalo Bills
7
41
03.12.01
NFL
San Francisco 49ers
Buffalo Bills
35
0
Buffalo Bills, last matches
San Francisco 49ers, last matches
11.09.26
NFL
Los Angeles Rams
San Francisco 49ers
7
27
28.08.26
NFL
Las Vegas Raiders
San Francisco 49ers
12
18
21.08.26
NFL
Los Angeles Chargers
San Francisco 49ers
17
41
14.08.26
NFL
San Francisco 49ers
Tennessee Titans
13
19
18.01.26
NFL
Seattle Seahawks
San Francisco 49ers
41
6
11.01.26
NFL
Philadelphia Eagles
San Francisco 49ers
19
23
Los Angeles Rams
San Francisco 49ers
7
27
28.08.26
NFL
Las Vegas Raiders
San Francisco 49ers
12
18
21.08.26
NFL
Los Angeles Chargers
San Francisco 49ers
17
41
14.08.26
NFL
San Francisco 49ers
Tennessee Titans
13
19
18.01.26
NFL
Seattle Seahawks
San Francisco 49ers
41
6
11.01.26
NFL
Philadelphia Eagles
San Francisco 49ers
19
23
Where they stand
| # | Club | P | GD | Pts |
|---|---|---|---|---|
| 1 | Buffalo Bills |
— | 15 | — |
| 2 |  Baltimore Ravens |
— | 18 | — |
| 3 |  Jacksonville Jaguars |
— | 24 | — |
| 4 |  Kansas City Chiefs |
— | 21 | — |
| 5 | Las Vegas Raiders |
— | 14 | — |
| 6 |  New York Jets |
— | 13 | — |
| 7 |  Cincinnati Bengals |
— | 6 | — |
| 8 |  Pittsburgh Steelers |
— | 7 | — |
| 9 |  Houston Texans |
— | -5 | — |
| 10 |  Indianapolis Colts |
— | -18 | — |
| 11 |  Miami Dolphins |
— | -14 | — |
| 12 | Tennessee Titans |
— | -13 | — |
| 13 |  Denver Broncos |
— | -21 | — |
| 14 |  Cleveland Browns |
— | -24 | — |
| 15 | Los Angeles Chargers |
— | -12 | — |
| 16 |  New England Patriots |
— | -3 | — |
| 1 |  Minnesota Vikings |
— | 17 | — |
| 2 |  New York Giants |
— | 8 | — |
| 3 | San Francisco 49ers |
— | 20 | — |
| 4 |  Chicago Bears |
— | 22 | — |
| 5 | Philadelphia Eagles |
— | 2 | — |
| 6 |  Arizona Cardinals |
— | 12 | — |
| 7 | Seattle Seahawks |
— | 3 | — |
| 8 |  Detroit Lions |
— | -9 | — |
| 9 |  Carolina Panthers |
— | -22 | — |
| 10 |  Washington Commanders |
— | -2 | — |
| 11 |  Green Bay Packers |
— | -17 | — |
| 12 |  Dallas Cowboys |
— | -8 | — |
| 13 | Los Angeles Rams |
— | -20 | — |
| 14 |  Tampa Bay Buccaneers |
— | -6 | — |
| 15 |  Atlanta Falcons |
— | -7 | — |
| 16 |  New Orleans Saints |
— | -1 | — |